156 CMAAO CORONA FACTS and MYTH Reducing mortality in ICU in COVID 19
Dr K Aggarwal
President CMAAO
With inputs from Dr Monica Vasudev
991: COVID-19 Death Rates in ICUs Down to
less than 41.6%
Overall mortality of patients with COVID-19 in intensive
care units (ICUs) across Europe, Asia, and North America has dropped from
nearly 60% at the end of March to nearly 42% at the end of May, according to a
systematic review and meta-analysis. The study by R. A. Armstrong, a fellow at
Severn Deanery in Bristol, United Kingdom, and colleagues was published online
July 15 in Anaesthesia. It is the first systematic review and meta-analysis of
outcomes of patients with COVID-19 in ICUs.
The study searched the MEDLINE, EMBASE, PubMed, and Cochrane
databases for studies through May that reported ICU mortality for adult
patients admitted with COVID-19. The primary outcome measure was death in an
ICU as a proportion of completed ICU admissions. They found 24 relevant
observational studies, which included 10,150 patients. They calculated that
combined ICU mortality across all the studies was 41.6%, down by about one
third from the 59.5% ICU mortality seen in the studies to the end of March. The
lower mortality rate is still nearly twice the 22% mortality seen in ICU
admissions for other viral pneumonias. They note that mortality is not significantly
different across the three continents.
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