188 CMAAO CORONA FACTS and MYTH COVID Preexisting Heart Disease
Dr K Aggarwal
1054: Meta-analysis evaluates impact of cardiovascular risk profile on COVID-19 outcome
1. Patients with coronavirus disease 2019 (COVID-19) with cardiovascular comorbidities or risk factors are more likely to develop cardiovascular complications while hospitalised for COVID-19 and have a higher mortality risk, according to a study published in PLOS One.
2. Jolanda Sabatino, MD, "Magna Graecia" University, Catanzaro, Italy, and colleagues analysed data from 21 published observational studies on a total of 77,317 patients hospitalised for COVID-19 in Asia, Europe, and the United States.
3. Mean age was 48.4±18.5 and 40.41% of the hospitalised patients were females.
4. 12.89% had cardiovascular comorbidities, 36.08% had hypertension, and 19.45% had diabetes.
5. 10.74% of patients were smokers while obesity was present in 33.78%.
6. Coronary artery disease and heart failure were reported in 11.67%, 9.35% of patients, respectively, at presentation.
7. 5.30% had a history of chronic obstructive pulmonary disease.
8. Cardiovascular complications were registered during the hospital stay of 14.09% of patients. The most common of these complications were arrhythmias (18.40%) and myocardial injury (10.34%).
9. Pre-existing cardiovascular comorbidities or risk factors were significant predictors of cardiovascular complications (P = .019)
10. Age (P < .001), pre-existing cardiovascular comorbidities or risk factors (P < .001) and the development of cardiovascular complications during COVID-19 period (P = .038) were significant predictors of death.