Showing posts with label drug. Show all posts
Showing posts with label drug. Show all posts

Saturday, June 27, 2020

136 CMAAO CORONA FACTS and MYTH BUSTER Mortality Reduction in CMAAO countries Drug Protocol for Treating Doctors


136 CMAAO CORONA FACTS and MYTH BUSTER Mortality Reduction in CMAAO countries Drug Protocol for Treating Doctors

Dr K Aggarwal
President CMAAO



1.      Evidence of fever, hyper immune inflammatory response (High ESR, CRP or ferritin): Tab HCQS (hydroxychloroquine) 400mg 1 tab twice on first day, 400mg 1 tab once a day based on acute phase reactants response

2.      Tab Doxycycline (DOXT) 200 mg first day and 100 mg from day 2 to 7 Or Azithromycin 500 mg daily for five days. (Antibiotic with anti-viral response)

3.       Anti-parasitic Tab Ivermectin 12 mg I tablet once only (by all family)

4.      If severe hypoxia or pneumonia with very high D Dimer and Ferritin give IL-6 pathway inhibitors (Actrmra 400 mg 50K) IV: 8 mg/kg as a single dose (NIH 2020b; NIH 2020e).


5.       In high risk cases in first three days of onset: Favipiravir or Fabiflu 1600 mg twice daily on day 1, followed by 600 mg twice daily for a total duration of 7 to 14 days (Cai 2020; NIH 2020a).


6.      Inj Clexane 0.6 Ml OD or BID in all above age 58, heart patients, hypertension, diabetes, heart failure, asthma, COPD, post cancer, on Oxygen, sudden drop of oxygen on rest or exertion

7.      Prednisolone 1 mg per kg stat if sudden development of hypoxia on exertion or rest (3-7 days)

8.      Ing Remdesivir (Cipla) 200 mg day 1 and 100 mg day 2-5 at the development of oxygen requirement

9.      Sleep prone on your abdomen

10.   Prone oxygen by oxygen concentrator, minimum rate to get 92-96% oxygen levels

11.  Vitamin D Cap D-Rise 2000 IU once a day for three months

12.   Elemental Zinc 75 mg daily

13.  Vitamin C 500 mg twice daily for three days and then 500 mg daily

14.  Tab Ranitidine 150 mg twice daily till the duration of illness

15.   Tab Meftal 200 mg or Naprosyn 500 mg or Indomethacin 25 mg or Nice 100.

16.  SpO2 and Pulse monitoring regularly, especially day 4-7 three times daily.

17.   Inform your local authorities, if COVID positive.

18.   Inform if Temp >1030F or lasts >14 days or Breathlessness, SpO2 falls by >4 after six minutes walking, persistent chest pain

19.   Sudden loss of smell and taste is not a serious sign, may persist for some time, may come and go, may come before fever

20.  Conjunctivitis may occur in one eye and is not a serious sign

21.  Rash may occur on any part of body (more in women) and is not a serious sign

22.  Pus cells may be present in urine, indicate cystitis and not secondary infection (TLC will remain low)

23.   Monocytes presence indicates high viral response

24.  High CRP > 100 means very high inflammatory response

25.  Loose motions (70% women) means super spreader and often a mild sign. May come and go. Take ORS.

26.   Whole family may get COVID or COVID like illness, all may have different symptoms, atleast one will get loose motions

27.  All should do betadine povidone iodine gargles twice daily and povidone iodine nasal wash

28.   Get CBC with ESR, CRP, LDH on day 1 and day 5 onwards every third day

29.   If Lymphocyte count is low ( < 1000) LOPIMUNE one twice day for two weeks ( Ritinovir and Lopinovir)


30.   Review with reports at hcfimedicalreports@gmail.com

31.   9th day onwards you have non replicative virus and cannot pass on the infection to others

32.   RTPCR test may remain positive for up to 48 days

33.   Those who are 65 plus or have underlying diabetes or heart disease should wear three layered fabric mass

34.   Join daily zoom session at 8am (ID drkkaggarwal)



Monday, December 16, 2019

Nutraceutical or a drug


Nutraceutical or a drug

Dr KK Aggarwal
President CMAAO and HCFI

Experts from Central Drugs food Standard Control Organisation (CDSCO) and the Food Safety and Standards Authority of India (FSSAI) are debating how to decide a product as a drug or food. Most companies like to launch a food supplement to escape the price control.

The blurred line between drug and supplements surfaced in 2009 when the drug price regulator National Pharmaceutical Pricing Authority (NPPA) said that pharma firms are marketing drugs as food supplements to escape the price control.

The joint expert committee of CDSCO and FSSAI formed is meant to ascertain whether the products and ingredients marketed are labelled on the basis of their intended effects on the human body and further to be classified as drugs, vitamins or food.

Submissions be experts say that vitamins need to be allowed

both in health and nutritional supplements if they are within the recommended dietary allowance (RDA) stipulated by Indian Council of Medical Research (ICMR).

It further elaborates that the issue is more of recognizing RDA as the basis and not the ceiling in daily intakes of nutrients.

The submission recommends that vitamins should be allowed both in food as well as drug, depending on the dosages  employed. [Pharmabitz]

Saturday, February 2, 2013

Ask Dr. KK:My triglyceride levels are 300 mg%. Do I need a drug?


Answer: For first three months, try not taking white rice, white maida and white sugar. Stop alcohol if you take. Recheck after three months. There are 90% chances that your triglycerides will become normal.

Wednesday, August 3, 2011

AskDrKK:What happens after cessation of the drug?


Dr KK Answers: In most, resolution of drug fever will occur within 72 to 96 hours of discontinuing the offending drug.

AskDrKK: What are the lab abnormalities in drug fever?


Dr KK Answers:
1.    The white blood cell count can be elevated with accompanying eosinophilia
2.    The ESR is usually increased
3.    Liver and renal dysfunction
4.    Urine can be checked for eosinophils especially in interstitial nephritis caused by beta-lactam antibiotics.

AskDrKK: What is fever associated with drug administration?


Dr KK Answers:
a.    Solutions containing drugs can become contaminated with endotoxin or other exogenous pyrogens.
b.    Fever can also accompany a chemical phlebitis
c.    Fever can follow after injections with paraldehyde, pentazocine, and other drugs.
d.     Many routine vaccinations are associated with low-grade fever for 48 hours or less.
e.     Amphotericin B and bleomycin have pyrogenic properties. 

Wednesday, July 20, 2011

Dr KK Answers: Is ORS a drug?

 Oral rehydration solution was developed following the realization that, in many small bowel diarrheal illnesses, intestinal glucose absorption via sodium-glucose co-transport remains intact.
In diarrheal disease caused by organisms that depends on small bowel secretory processes, the intestine remains able to absorb water if glucose and salt are also present to assist in the transport of water from the intestinal lumen.