In a meta-analysis of 9 trials (387 pts) addition of plasma exchange decreased the risk of end-stage renal disease or death resulting from granulomatosis with polyangiitis (Wegener’s).
In January 2011, the Boards of Directors of the American College of Rheumatology, the American Society of Nephrology, and the European League Against Rheumatism recommended that the name Wegener’s granulomatosis be changed to “granulomatosis with polyangiitis (Wegener’s)”, abbreviated as GPA.