Dr KK Answers: Should diabetics take anti BP drug at bedtime or in the morning?

In a prospective, randomized open-label among diabetics treatment with anti BP drugs at bedtime, compared with drugs upon waking resulted in improved ambulatory blood pressure control and significantly reduced cardiovascular morbidity and mortality. There was a significant 12% cardiovascular risk reduction per each 5 mmHg decrease in asleep systolic blood pressure during follow-up (P < 0.001).

Source: Diabetes Care 2011 Jun; 34(6):1270-6.