Thursday, July 21, 2011

Emedinews: Dr Good Dr Bad: A patient with pneumonia

Situation: A 39–year–old male with community–acquired pneumonia came for OPD treatment.
Dr Bad: You need admission for IV ceftriaxone therapy.
Dr Good: Take Levofloxacin 500 mg orally.
Lesson: A prospective, randomized, multicenter trial of 599 adults with community-acquired pneumonia who could be treated as an outpatient or in the hospital compared the efficacy of levofloxacin (500 mg IV or orally daily) to ceftriaxone (1 to 2 g IV once or twice daily) and/or cefuroxime (500 mg orally twice daily) with or without erythromycin or doxycycline. Clinical success at 5 to 7 days after treatment was superior with levofloxacin (96%) compared with either cephalosporin arm (90%)

Ref: Antimicrob Agents Chemother 1997;41(9):1965–72.

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