Saturday, February 16, 2019

Physiological age is a better predictor of longevity than actual age: Exercise more to live longer

New research from the Cleveland Clinic has found that estimated “physiological” age based on exercise stress testing performance i.e. “how well you respond to exercise” is a better predictor of mortality when compared to chronological (actual) age. 

And, you can now calculate your physiological age based on your exercise performance during an exercise stress test using the formula “A-BEST” (Age Based on Exercise Stress Testing).

The formula takes into account three factors: Exercise capacity, how the heart responds to exercise (chronotropic competence) and how the heart rate recovers after exercise.

The study included 126,356 patients, who were referred to the Cleveland Clinic between 1991 and 2015 for their first exercise stress test. The average age of study participants was 53.5 years and 59% were men.

The individual components of A-BEST were each associated with mortality. After an average follow-up of 8.7 years, A-BEST was a significantly better predictor of survival than chronological age, even after adjusting for sex, smoking, body mass index, statin use, diabetes, hypertension, coronary artery disease and end-stage kidney disease. Fifty-five percent of males and 57% of females between the ages of 50 and 60 years had their estimated age younger than their chronologic age.

These findings are published online Feb.13, 2019 in the European Journal of Preventive Cardiology

Rather than the results of the components considered individually, calculating the physiological age of their patients will help clinicians to motivate their patients to exercise more and stay fit as it provides an estimate of longevity.

It’s like a wake-up call, which makes one realize the need to take necessary action to remedy the situation.

Exercise more to live longer….

(Source: ESC Press release, Feb.14, 2019; Eur J Prev Cardiol. 2019 Feb 13)  

Dr KK Aggarwal
Padma Shri Awardee
President Elect Confederation of Medical Associations in Asia and Oceania   (CMAAO)
Group Editor-in-Chief IJCP Publications
President Heart Care Foundation of India
Past National President IMA

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