Showing posts with label virus. Show all posts
Showing posts with label virus. Show all posts

Friday, July 3, 2020

142 CMAAO CORONA FACTS and MYTH BUSTER: G4 EA H1N1



142 CMAAO CORONA FACTS and MYTH BUSTER: G4 EA H1N1


Dr K Aggarwal
President CMAAO

964: G4 New hybrid Flu Virus in Pigs with Pandemic Potential:  G4 EA H1N1
1. A new flu virus (hybrid) found in Chinese pigs has features that make it more infectious to humans and needs to be watched closely in case it becomes a potential pandemic virus.
2.  A team of Chinese researchers looked at influenza viruses found in pigs from 2011 to 2018 and found a "G4" strain of H1N1 that has "all the essential hallmarks of a candidate pandemic virus", according to the report in the Proceedings of the National Academy of Sciences 
3. G4 includes sequences from a virus discovered in birds in Europe and Asia, as well as the one that caused the 2009 H1N1 pandemic, which was a hybrid of human, swine and bird flu viruses.
4.  Pig farm workers also showed elevated levels of the virus in their blood.
5.  Pigs are considered important "mixing vessels" for the generation of pandemic influenza viruses
6.  China took action against an outbreak of avian H1N1 in 2009, restricting incoming flights from affected countries and putting tens of thousands of people into quarantine.
7.  The new virus identified in the study is a recombination of the 2009 H1N1 variant and a once prevalent strain found in pigs.
8.  But while it is capable of infecting humans, there is no imminent risk of a new pandemic.
9.  There's no evidence that G4 is circulating in humans, despite five years of extensive exposure.
10. Are these experimental viruses?




Wednesday, March 25, 2020

CMAAO IMA HCFI CORONA MYTH BUSTER 15


Last in  the series
From now onwards we will start fact series

CMAAO IMA HCFI CORONA MYTH BUSTER 15

Dr K K Aggarwal
President CMAAO, HCFI and Past National President CMAAO

CT chest is the test of choice

No, as CT can be normal in early illness, and after each potentially infected patient is scanned, the machine must be completely disinfected. Therefore, CT isn't recommended to screen for COVID-19.

Should doctors maintain physical distance with their colleague in the healthcare setting?
Yes. 10% of the health care workers get  covid 19 and one of the main mode of transmission is cross infection amongst each other.

Anosmia is as common as in flu
A growing body of data from COVID-19 patients in several countries strongly suggests that "significant numbers" of those patients experienced anosmia as one of the disease's symptoms, according to the ENT UK statement. 

Anecdotal evidence further describes the loss of smell and the loss of taste — known as dysgeusia — in people who had no other symptoms but who tested positive for COVID-19, representatives of the American Academy of Otolaryngology–Head and Neck Surgery (AAO–HNS) in Alexandria, Virginia, said in a March 22 statement.

Is COVID 19 a occupational hazard amongst health care workers
As per WHO, Yes.

Should we nebulize a person with COVID ARI

No, use spacer and not nebulizer. It can produce aerosol and be infective to others.

Should we use high flow  oxygen to a person with COVID ARI

No, use low flow. It can produce aerosol and be infective to others.

Should we non invasive ventilation to  a person with COVID ARI

No, use invasive ventilation. NIV can produce aerosols and be infective to others. But if invasive ventilators are not available use them.

One ventilator two pateiunts, let one die

No. necessity is the mother of invention. Share one ventilator for more than one patient. Detroit, Michigan demonstrates in a YouTube video. She responded that a filter is placed before the expiration port connection with the T-piece and it's a 1-way circuit. She noted that the tubing is 5 feet from the endotracheal tube.


CPR should not be done kin dying COVID patients

The AHA advises
  • Aerosol-generating procedures such as CPR and endotracheal intubation expose providers to a greater risk of disease transmission and should be performed in airborne infection isolation rooms (AIIRs); personnel should use respiratory protection.
  • Only providers essential for patient care and procedural support should be present during the procedure and the room should be cleaned and disinfected following the procedure.
  • Patients with known or suspected COVID-19 should be cared for in a single-person room with the door closed and AIIRs should be reserved for patients undergoing aerosol-generating procedures.
  • N95 respirators or respirators that offer a higher level of protection should be used instead of a face mask during aerosol-generating procedures.
  • Providers should put on a respirator or facemask (if a respirator is not available) before entering a patient's room or care area. Facilities should return to use of respirators for patients with known or suspected COVID-19 once the supply chain is restored.
  • Wear eye protection, gloves, and gowns.
  • When gowns are in short supply, they should be prioritized for aerosol-generating procedures, care activities where splashes and sprays are anticipated, and high-contact patient care activities that provide opportunities for transfer of pathogens to the hands and clothing of providers.
  • If intubation is needed, consider using rapid sequence intubation with appropriate personal protective equipment (PPE).
  • If possible, avoid procedures which generate aerosols, such as bag-valve mask, nebulizers and non-invasive positive pressure ventilation.
  • Consider proceeding directly to endotracheal intubation in patients with acute respiratory failure. Avoid the use of high-flow nasal oxygenation and mask CPAP or bilevel CPAP due to greater risk of aerosol generation.


Liver involvement is mild

No. Individuals at high risk for severe COVID-19 are typically of older age and/or present with comorbid conditions such as diabetes, cardiovascular disease, and hypertension. This is also the same profile for those at increased risk for unrecognized underlying liver disease, especially nonalcoholic fatty liver disease. This could make them more susceptible to liver injury from the virus, medications used in supportive management, or hypoxia.

According to a report published in 2014 up to 60% of patients with SARS had liver impairment, with liver biopsy specimens demonstrating viral nucleic acids and injury.

This may have been the result of drug-induced liver injury, given that most of these patients were treated with high doses of potentially hepatotoxic antivirals, antibiotics, and steroids.

Peripheral ground-glass opacities are not specific for COVID 19 on CT chest

Although they are sensitive but not specific for coronavirus as it can also occur in Pneumocystis jirovecii pneumonia, cryptogenic organizing pneumonia, and acute lung injury from drug toxicity, hypersensitivity, and autoimmune diseases. But these causes are uncommon. In todays , COVID era this picture can be taken as diagnostic.



Tuesday, February 25, 2020

International Travel during Corona Period: CMAAO Guidelines

International Travel during Corona Period: CMAAO Guidelines

Dr K K Aggarwal
President CMAAO, HCFI AND Past National President IMA

The present diamond princess ship with corona outbreak has shown us to revisit our travel checklist when visiting any country

Travel advisory are of four types

Level 1 in all countries (Exercise normal standard hygiene precautions)

Level 2 in all affected countries (Exercise a high degree of caution)

Level 3 in all countries with secondary cases (Reconsider your need to travel)

Level 4 in affected parts of China and Korea (Do not travel) 

1. Keep the possibility of being quarantined for 14 days in any country.

2. Carry atleast 20 days extra essential medicines stock.

3. Always keep the passport, kept in a plastic pouch, in a safew front pocket, with you in case you need to leave the country in emergency.

4. Always carry your medicines authentic prescription with you with generic names of the drugs.

5. Always carry some dry fruits with you.

6. Always book a refundable air ticket even if they are 10% costlier.

7. Always carry a photocopy of passport and visa.

8. Always get travel insurance. Remember most standard policies won't cover you for 'Do not travel' destinations.

9. Understand that you could die. Make sure you have an up-to-date will, an enduring power of attorney. Designate appropriate insurance beneficiaries.

10. Never travel to countries with level 4 warnings ( do not travel) like for Wuhan in China.

11. For level 3 warning (like currently India for Singapore), travel only if must, minimise time spent in airports by scheduling direct flights if possible. Avoid stopovers in high-risk airports.  Stay as short a time as possible. Eliminate unnecessary activities.

12. Leave an area at the first sign of unrest, or if you feel uneasy.



Tuesday, February 18, 2020

Concern of COVID 19 outside China


Concern of COVID 19 outside China
Dr K K Aggarwal
President CMAAO, HCFI and Past National President IMA
18th Feb: Four deaths outside China including a man in Taiwan with no history of travel to mainland China. 

Serious or critical cases in China 11741. Other than China 54 critical cases are: (Diamond Princess 19, Singapore 4, Japan 19, Hong Kong 7, Thailand 2, UAE 1, Italy 2). Likely deaths outside China will be 54X15%= 8

Total expected deaths outside china will be 12 (8+4). With the current situation.  
Search:
Country,
Other

Total Cases
New
Cases
Total
Deaths
New
Deaths
Total
Recovered
Serious,
Critical
China
72,436
+1,888
1,868
+98
12,552
11,741
Diamond Princess
454
17
19
Singapore
77
24
4
Japan
66
1
18
19
Hong Kong
60
1
2
7
Thailand
35
15
2
S. Korea
31
+1
10
Taiwan
22
1
2
Malaysia
22
9
Germany
16
7
Vietnam
16
7
Australia
15
10
USA
15
3
France
12
1
5
Macao
10
5
U.A.E.
9
3
1
U.K.
9
8
Canada
8
1
Philippines
3
1
2
Italy
3
2
India
3
3
Russia
2
2
Spain
2
2
Egypt
1
Cambodia
1
1
Sweden
1
Nepal
1
1
Belgium
1
1
Sri Lanka
1
1
Finland
1
1