Emedinews: TEMPI, a new mysterious, life-threatening blood disease affecting kidneys

Harvard Medical School and the University of Southern California doctors are going public to seek new cases of a mysterious, life-threatening blood disease.

Doctors have identified three people in the world with the syndrome, which worsens over time and causes painful fluid buildup around the kidneys, shortness of breath that can require oxygen, dilated blood vessels under the skin and spontaneous bleeding in the brain.

Three more potential cases of the TEMPI syndrome, have been previously reported in medical literature, the researchers wrote in the New England Journal of Medicine"

The disease does not seem to be caused by cancer, infection, or by genetics, but could have a correlation to a particular abnormal antibody protein discovered in all three patients' blood.