Folic acid supplementation decreases homocysteine (Hcy) levels in individuals with type 2 diabetes patients under metformin treatment, according to a study published in the journal Diabetes Research and Clinical Practice.
The researchers found that eight weeks of 5 mg folic acid supplementation led to a significant decrease in levels of insulin, HOMA-IR, and HbA1c (16.2%, 20.5%, and 7.5%, respectively). There was also a substantial 21.2% drop in Hcy levels and a 7.5% reduction in FBG in the FA group when compared to the placebo group.
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