Premature or early heart attacks is when a man gets it before age 55 or a woman before age 65, said Padma Shri and Dr B C Roy National Awardee Dr KK Aggarwal, President Heart Care Foundation of India & MTNL Perfect Health Mela. The mean age for premature heart attack is 53–54 yrs.
Family history means when any of the first-degree relative i.e. father, mother, brother, sister had suffered from an earlier or premature heart attack.
Having one first degree relative with a heart attack below age 55 increases the risk in the subsequent generation by 33% and two relatives increase the risk by 50%.
In addition, the offspring of patients with premature heart disease are more likely to have coronary risk factors than those without such a family history. These include excess body weight and elevations in higher levels of serum cholesterol, glucose, and insulin. These offspring are also more likely to have evidence of vascular disease such as endothelial dysfunction and increased carotid artery intima-media thickness.
Younger patients with heart disease more often have a family history of premature heart disease.
It is estimated that a family history unrelated to conventional risk factors can account for 15 percent of heart attacks.
Compared to no parental history of a heart attack, a maternal history, a paternal history, and both maternal and paternal history are associated with a relative risk of future heart attack of 1.71, 1.40, and 1.85 in men and 1.46, 1.15, and 2.05 in women.
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