After about 11 years, the daily multivitamin use resulted in an 8% reduction in total cancer incidence in men according to the results of a very large randomized trial by John Michael Gaziano, MD, MPH from Harvard at the Annual American Association for Cancer Research (AACR) Frontiers in Cancer Prevention Research meeting and also published in JAMA. Cancer mortality also went in 12% reduction.
Previous studies have reported conflicting results. As reported by Medscape Medical News, two studies evaluating the association of multivitamins and breast cancer found opposite results — one study found an increased risk while the other found that multivitamins decreased the risk. Another study reported more neutral results, in that multivitamin use had no influence on the risk for common cancers, cardiovascular disease, or overall mortality.
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