A meta-analysis of 10 randomized trials compared probiotics (strains of lactobacilli, bifidobacterium, and propionibacterium) with placebo for the prevention of upper respiratory tract infections showed that probiotics decreased the rate of acute respiratory infections but they had no significant effect on the duration of symptoms.
Higher-quality trials that include older adults are needed before it can be determined whether probiotics have a role in the prevention of respiratory tract infections in adults. [Cochrane Database Syst Rev 2011; :CD006895.]
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